Weight, biochemical parameters, insulin resistance index and inflammatory markers in an obese rat model of type 2 diabetes after 52 weeks of treatment with lithospermic acid B or with saline as control.

Key: AUCglucose, Area under the curve of glucose; HDL, high-density lipoprotein; HsCRP, high-sensitivity C-reactive protein; HOMA-IR, homeostasis model assessment of insulin resistance; LDL, low-density lipoprotein; MCP1, monocyte chemotactic protein-1; PAI1, plasminogen activator inhibitor-1; TNFα, tumor necrosis factor-alpha; 8-OHdG, 8-hydroxy-2′-deoxyguanosine. †ANOVA with post hoc test (Tukey's b) was used. A, B and C superscripts indicate significant differences between pairs of groups: A, Control vs. 10 mg/kg LAB group; B, Control vs. 10 mg/kg LAB group; C, 10 mg/kg LAB vs. 20 mg/kg LAB groups; P