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Effects of ZAKalpha on UVB-dependent trancriptional changes in N/TERT-1 cells

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE251957
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This study investigates the effect of ZAKalpha kinase in UVB-triggered signaling in an immortalized keratinocyte cell line N/TERT-1. The experiments compared sham-irradiated and UVB-irradiated isogenic Cas9 control and ZAK KO cells in order to define which UVB responsive transcripts are controlled by ZAKalpha. Isogenic Cas9 control and ZAK KO N/TERT-1 cells are either sham irradiated or UVB-irradiated (100mJ2/cm2). All cells were harvested 4 hours after irradiation.
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2025-01-30
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