Vitamin C boosts DNA demethylation in TET2 germline mutation carriers
收藏NIAID Data Ecosystem2026-03-14 收录
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We recently identified a family with lymphoma predisposition where a heterozygous truncating germline mutation in TET2 segregated with nodular lymphocyte predominant Hodgkin lymphoma. In a clinical trial of one year, we investigated the effects of oral 1 g/day vitamin C supplementation on DNA methylation by analyzing genome-wide DNA methylation and gene expression patterns from the family members.EGA study EGAS00001006916
创建时间：
2023-02-01
