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BCOR controls maintenance of haematopoietic stem cell quiescence and regulates myeloid cell proliferation and differentiation

ChEBI2015-12-31 更新2026-07-12 收录

造血干细胞静息

髓系细胞分化

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-69624 数据链接链接失效反馈

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BCOR controls maintenance of haematopoietic stem cell quiescence and regulates myeloid cell proliferation and differentiation

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2015-12-31

造血干细胞静息

血液系统再生机制

The transcription factor hepatic leukemia factor (HLF) is highly expressed in hematopoietic stem cells (HSCs) and has been proposed to influence both HSC self-renewal and leukemogenesis. However, the

NIAID Data Ecosystem70

The transcription factor EGR2 is indispensable for tissue-specific imprinting of alveolar macrophages in health and tissue repair [myeloid cells]

单细胞转录组学

髓系细胞分化

We profile the transcriptomes of over 3,000 mouse single myeloid cells from mouse lung to define the transcriptional profiles of monocytes and subsets of dendritic cells and macrophages. We perform d

NIAID Data Ecosystem50

Reduced representation bisulfite sequencing (RRBS) profiling of ER-Hoxa9-Lys-GFP cells over myeloid differentiation program

DNA甲基化分析

髓系细胞分化

Data reveal epigenome-wide trends associated with progression from the GMP-like state to the neutrophil-like state ER-Hoxa9 cells cultured with estradiol, 120 hours without estradiol, or with estradio

NIAID Data Ecosystem30

Transforming growth factor beta upregulates 5-lipoxygenase activity during myeloid cell maturation.

髓系细胞分化

5-脂氧合酶活性调控

Transforming growth factor beta (TGF beta) increased the arachidonate 5-lipoxygenase (5-LO; EC 1.13.11.34) activity in HL-60 cells induced to granulocytic differentiation by dimethyl sulfoxide. The pr

PubMed Central1993-07-01 更新50

Data_Sheet_1_Bone Marrow Plasma Cells Modulate Local Myeloid-Lineage Differentiation via IL-10.PDF

免疫调控机制

髓系细胞分化

Bone marrow plasma cells have been reported to represent a major source of IL-10; however, the impact of plasma cell derived IL-10 in that tissue remains poorly understood. We confirm in this study th

NIAID Data Ecosystem40

BCOR controls maintenance of haematopoietic stem cell quiescence and regulates myeloid cell proliferation and differentiation

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