The CH1 protein interaction domain of the transcriptional coactivators p300 and CBP is thought to interact with HIF-1alpha and this interaction is thought to be critical to the expression of HIF-1alph

NIAID Data Ecosystem60

Identification of hypoxia target genes in human CB CD34+ cells

低氧反应基因调控

干细胞分子机制

Although it has been shown that HIF1 and 2 fulfill essential roles within the hematopoietic system and in the regulation of HSC fate, little is currently known about the specific mechanisms that are i

NIAID Data Ecosystem30

Genome Wide Expression Analysis Suggests Perturbation of Vascular Homeostasis during High Altitude Pulmonary Edema

肺水肿分子机制

脑血管基因表达调控

Background High altitude pulmonary edema (HAPE) is a life-threatening form of non-cardiogenic edema which occurs in unacclimatized but otherwise normal individuals within two to four days after rapid

NIAID Data Ecosystem60

Twist1 Controls Lung Vascular Permeability and Endotoxin-Induced Pulmonary Edema by Altering Tie2 Expression

肺血管通透性调控

肺水肿分子机制

Tight regulation of vascular permeability is necessary for normal development and deregulated vascular barrier function contributes to the pathogenesis of various diseases, including acute respiratory

NIAID Data Ecosystem40

Genes involved in early responses to hypoxia.

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