An N‑Heterocyclic Carbene-Nickel Half-Sandwich Complex as a Precatalyst for Suzuki–Miyaura Coupling of Aryl/Heteroaryl Halides with Aryl/Heteroarylboronic Acids

A nickel
half-sandwich complex supported by our original NHC ligand
was developed as a robust precatalyst for Suzuki–Miyaura cross-coupling.
The addition of PPh3 was a crucial element in the suppression
of side reactions and in accelerating the cross-coupling reaction.
By employing the optimal conditions, aryl–aryl, heteroaryl–aryl,
and heteroaryl–heteroaryl couplings were achieved.