Compartment specific misfolding induced stress in Saccharomyces cerevisiae. Saccharomyces cerevisiae S288C

RNA SEQ was performed for the yeast cells expressing different model proteins (MBP(Maltose Binding Protein), DMMBP (Double mutant form of MBP), DHFR(Dihydrofolate reductase), mutC-DHFR(mutant form of DHFR), PMD(Protein with misfolded domain)) under galactose inducible promoter targeted to various sub-cellular compartments like Endoplasmic reticulum(ER), Nucleus(NUC), Cytosol(CYTO), Mitochondrial matrix(MM) and Mitochondrial Intermembrane Space(IMS)