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Synthesis of Indolizines via Palladium Catalyzed Annulation of Propargyl Carbonates and 2‑(Pyridin-2-yl)acetonitrile Derivatives

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NIAID Data Ecosystem2026-03-10 收录
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https://figshare.com/articles/dataset/Synthesis_of_Indolizines_via_Palladium_Catalyzed_Annulation_of_Propargyl_Carbonates_and_2_Pyridin-2-yl_acetonitrile_Derivatives/5491393
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A Pd-catalyzed regioselective annulation reaction of propargyl carbonates and 2-(pyridine-2-yl) acetonitrile derivatives has been accomplished, which provides a straightforward and efficient access to polysubstituted indolizines. The choice of the phosphine ligand is crucial to the high regio-selectivity of the reaction.
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2017-10-11
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