A comparative summary of IN-DNA S-S crosslinking with mixed disulfide–modified substrates.

The efficiency of crosslinking is shown by a number of (+) signs. The most efficient contact sites are shown in bold (++). The DNA substrates used are shown in the top row; d* indicates preference for dimer formation. Linear(L) and Y-mer(Y) dsDNA substrates with thiol groups introduced in the bases of certain strand (e.g. L4 carries a modification in strand 4 (processed strand of viral end) at certain position (e.g. L3-12 is modified at 12th nucleotide from 5′-end of the non-processed strand, or L4-3 – at 3rd position (A) of processed strand that is next to scissile phosphate.