10x Single-Cell RNAseq Colon (Reference)

Human epithelial, B, and stromal cells from the colon in a SingleCellExperiment object with labels. These data can be used as a reference set for training cell-type annotation classifiers. These three different cell-types were combined from the following original studies: <br> Epithelial cells: Wang, Y., Song, W., Wang, J., Wang, T., Xiong, X., Qi, Z., ... &amp; Chen, Y. G. (2020). Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine. <em>Journal of Experimental Medicine</em>, <em>217</em>(2). <br> B cells: Huang, B., Chen, Z., Geng, L., Wang, J., Liang, H., Cao, Y., ... &amp; Zhang, Y. (2019). Mucosal profiling of pediatric-onset colitis and IBD reveals common pathogenics and therapeutic pathways. <em>Cell</em>, <em>179</em>(5), 1160-1176. <br> Stromal cells: Kinchen, J., Chen, H. H., Parikh, K., Antanaviciute, A., Jagielowicz, M., Fawkner-Corbett, D., ... &amp; Simmons, A. (2018). Structural remodeling of the human colonic mesenchyme in inflammatory bowel disease. <em>Cell</em>, <em>175</em>(2), 372-386.