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Aminodiols via Stereocontrolled Oxidation of Methyleneaziridines

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Figshare2015-12-17 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Aminodiols_via_Stereocontrolled_Oxidation_of_Methyleneaziridines/2030490
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A highly diastereoselective Ru-catalyzed oxidation/reduction sequence of bicyclic methyleneaziridines provides a facile route to complex 1-amino-2,3-diol motifs. The relative anti stereochemistry between the amine and the vicinal alcohol are proposed to result from 1,3-bischelation in the transition state by the C1 and C3 heteroatoms.
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2015-12-17
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