We characterize the transcriptomic profile of a set of human IgG1 and IgG4-switched memory B cell clones Overall design: mRNA profiles of human B cell clones were generated by deep sequencing
H-score = proportion score×intensity score. A total score of 0–12 was calculated and graded as negative (−, score:0), weak (+, score:1–4), moderate (++, score:5–8) or strong (+++, score:9–12).