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PMCA2 Regulates HER2 Expression, Cell-Surface Localization and Signaling, and Promotes HER2- Mediated Breast Cancer

ChEBI2014-10-22 更新2026-07-21 收录

乳腺癌分子机制

离子信号调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-62555 数据链接链接失效反馈

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资源简介：

PMCA2 Regulates HER2 Expression, Cell-Surface Localization and Signaling, and Promotes HER2- Mediated Breast Cancer

应用场景：

创建时间：

2014-10-22

转录因子结合分析

乳腺癌分子机制

In order to identify genes co-bound by SOX4 and SMAD3 in the context of breast cancer, different breast cell lines (HMLEs, MDA-MB-231 or HCC-1954) were used. Due to low endogenous expression levels fo

NIAID Data Ecosystem80

RNA-seq of FBXO7 knockdown in breast cancer cell line

乳腺癌分子机制

基因表达分析

RNA-seq of FBXO7 knockdown in breast cancer cell line RNA-seq analysis of FBXO7 knockdown in breast cancer cell line MDA-MB-231.

NIAID Data Ecosystem50

Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.. Dietary ligands diindolylmethane and resveratrol result in diverse ERα signaling not seen after E2 and a subset of diindolylmethane mediated signaling needs concurrent AHR activation.

乳腺癌分子机制

受体信号通路

Inhibitory crosstalk between estrogen receptor alpha (ER alpha ) and aryl hydrocarbon receptor (AHR) regulates 17-estradiol (E2)-dependent breast cancer cell signaling. ER alpha and AHR are transcript

NIAID Data Ecosystem40

Additional file 1: of Inferring miRNA sponge co-regulation of protein-protein interactions in human breast cancer

乳腺癌分子机制

RNA调控网络

BRCA-related miRNA sponge interaction network. The network includes 37076 miRNA sponge interactions. (XLSX 484Â kb)

NIAID Data Ecosystem70

The primer sequence.

乳腺癌分子机制

癌症药物靶点

BackgroundBreast cancer continues to be a predominant cause of female mortality globally, characterized by limited therapeutic options and substantial adverse effects. Artesunate (ART), a traditional

Figshare2025-08-04 更新40

PMCA2 Regulates HER2 Expression, Cell-Surface Localization and Signaling, and Promotes HER2- Mediated Breast Cancer

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