To identify host cell factors required for LACV entry, we used a lentiviral library of 4,630 single guide RNAs targeting 1,146 human genes that encode proteins predicted to be present on the plasma me
Synovial sarcoma (SySa) is an aggressive soft tissue sarcoma with an urgent need to develop targeted therapies. Here, we exploited specific vulnerabilities created by transcriptional rewiring by the f
Here, we describe CRISPRpath, a CRISPR screening strategy for simultaneously characterizing CREs in multiple genomic loci by leveraging converging phenotypes resulted from transcriptional defects in g
