Analysis of genome-wide hydroxymethylation within infant placental tissue collected at term. These samples have been collected from the RhodeIsland Child Health Study (RICHS) cohort. Overall design: B
DNA methylation data across 5x10^6 CpG loci, derived from buccal cells of 6-month-old infants. Method is bisulfite treatment followed by next-generation sequencing using Illumina SeqCap Epi Enrichment
Pre-pregnancy obesity is an established risk factor for adverse sex-specific cardiometabolic health in offspring. Epigenetic alterations, such as in DNA methylation (DNAm), are a hypothesized link; ho