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Data for the article entitled “Chitosan - zeolite scaffold as a potential biomaterial in the controlled release of drugs for osteoporosis”

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DataCite Commons2024-03-26 更新2025-04-16 收录
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https://repod.icm.edu.pl/citation?persistentId=doi:10.18150/0WT0IQ
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Files include the data presented in the manuscript entitled " Chitosan - zeolite scaffold as a potential biomaterial in the controlled release of drugs for osteoporosis" by M. Sandomierski et al. (https://doi.org/10.1016/j.ijbiomac.2022.11.071).In this work, chitosan‑calcium zeolite scaffolds were prepared and used in the controlled release of the drug for osteoporosis - risedronate. More drug was retained on the scaffold with the addition of zeolite compared to that with the hydroxyapatite. The new scaffolds have proven to be able to retain the drug and slowly release it in small doses. The results obtained are promising and show great potential for this material in bone tissue engineering. To our best knowledge no one has ever used this type of modification for bisphosphonate delivery.Data (.txt) includes:1) X-ray diffraction patterns of zeolite X and CaX. (Fig.2)2) Zeta potential curves of X and CaX zeolites. (Fig. 4.)3) Characteristics of materials based on nitrogen adsorption/desorption Measurements. (Table 1.)4) FTIR spectra of chitosan, chitosan-hydroxyapatite scaffold and chitosan-zeolite scaffold. (Fig. 7.)5) Drug sorption on the chitosan-hydroxyapatite scaffold and chitosan-zeolite scaffold. (Fig. 11.)6) Release of risedronate from the chitosan-hydroxyapatite scaffold and chitosan-zeolite scaffold. (Fig. 12.)
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2023-03-06
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