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A Naphthyl Sophorolipid Derivative Disrupts Mitochondrial Metabolic Control, Impairing Central Carbon Metabolism to Inhibit Filamentation in Candida albicans and Attenuates Systemic Infection

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Zenodo2026-04-06 更新2026-05-26 收录
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This file contains the raw data corresponding to all composite figures (Figures 1-8 and Supplementary Figures S1–S7) associated with the manuscript entitled “A Naphthyl Sophorolipid Derivative Disrupts Mitochondrial Metabolic Control to Inhibit Filamentation and Attenuate Systemic Infection in Candida albicans.” The dataset includes key results demonstrating antifungal activity, mitochondrial dysfunction (membrane potential loss and ATP depletion), disruption of central carbon metabolism, inhibition of yeast-to-hyphae transition and biofilm formation, and therapeutic efficacy in murine models. All figures represent raw data obtained from microbiological assays, imaging, molecular analyses, and in vivo experiments, serving as the primary source for the main and supplementary figures.

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Zenodo
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2026-04-06
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