Clinical characteristics and genomic alterations in NSCLC specimens.
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https://figshare.com/articles/dataset/_Clinical_characteristics_and_genomic_alterations_in_NSCLC_specimens_/448258
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Abbreviations: AD, adenocarcinoma; Bx, biopsy; CSF, cerebral-spinal fluid; Del, deletion in EGFR exon 19 (Del-1a: E746_A750_2235–2249del; Del-1b: E746_A750_2236–2250del); F, female; FF, Fresh-Frozen; FFPE, Formalin-fixed, paraffin-embedded; H&E, haematoxylin and eosin-stained tumor section; M, male; LN, lymph node; N/A, not applicable; MUT, mutation; PD, progressive disease; PR, partial remission; RL, relapse; SD, stable disease; SCLC, small cell lung cancer; SQ, squamous cell carcinoma; TKI, tyrosine kinase inhibitor; WT, wild-type EGFR and KRAS;
a)Tumor specimen obtained prior to TKI treatment.
b)Tumor specimen obtained after relapse from TKI treatment.
*Mutation detection sensitivity of dideoxy and pyrosequencing is limited due to rare tumor cell content possibly generating false-negative samples.
$Case 10 achieved a partial response to TKI treatment. However, the analyzed tumor specimen was obtained at the time of relapse and is therefore indicated as PR (partial remission) and RL (relapse).
创建时间：
2011-05-05
