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Data from: Disruption of memory reconsolidation erases a fear memory trace in the human amygdala: An 18-month follow-up

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DataONE2015-07-01 更新2024-06-27 收录
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This is data is from a fear conditioning experiment measuring skin conductance and fMRI BOLD, pertaining to the article: Björkstrand J, Agren T, Frick A, Engman J, Larsson EM, Furmark T, Fredrikson M. Disruption of memory reconsolidation erases a fear memory trace in the human amygdala: An 18-month follow-up, yet to be published. Please consult this article and the original study: “Agren T, Engman J, Frick A, Björkstrand J, Larsson EM, Furmark T, Fredrikson M. 2012. Disruption of reconsolidation erases a fear memory trace in the human amygdala. Science 337:1550-1552” , for details concerning the purpose and design of the study. In the folder SCRdataAndGroup you can find an excel file containing raw and range corrected skin conductance responses (SCR) for all subjects from the follow-up measurement 18 months after fear acqusition, as well as information as to which subject belongs to which group. In the folders named subject1-19 you can find SPM8 contrast files from the renewal session three days after acquisition. The contrast shows the BOLD response to the first CSplus trial over an immediate preceding baseline for each subject. These files can be used to perform second level analysis using SPM8 for Matlab. In the folder MaskForColocalizationAnalysis you can find the SPM8 image file used to perform the colocalization analysis described in the follow-up study.

本数据集来源于一项测量皮肤电导率与功能磁共振成像血氧水平依赖(fMRI BOLD)信号的恐惧条件反射实验,相关关联文献包括:Björkstrand J、Agren T、Frick A、Engman J、Larsson EM、Furmark T、Fredrikson M所著的《Disruption of memory reconsolidation erases a fear memory trace in the human amygdala: An 18-month follow-up》(暂未正式发表)。有关本研究的目的与实验设计的详细信息,请参阅该文献以及2012年发表于《Science》的原始研究:Agren T、Engman J、Frick A、Björkstrand J、Larsson EM、Furmark T、Fredrikson M所著的《Disruption of reconsolidation erases a fear memory trace in the human amygdala》(Science 337:1550-1552)。在SCRdataAndGroup文件夹中,可获取一份Excel文件,内含恐惧习得18个月后随访测量阶段所有受试者的原始皮肤电反应(SCR)数据与范围校正后数据,以及受试者所属分组信息。在名为subject1-19的文件夹中,可获取恐惧习得实验三天后复现测试阶段的统计参数映射8(SPM8)对比文件,该对比反映了每位受试者首次条件刺激阳性(CS+)试次相对于即刻前基线的血氧水平依赖响应,此类文件可用于基于Matlab平台的SPM8进行二级分析。在MaskForColocalizationAnalysis文件夹中,可获取用于随访研究中共定位分析(colocalization analysis)的SPM8图像文件。
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2015-07-01
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