HDACU

This data come from an observational, retrospective case-control study, according to the STROBE and STRICTA guides. The study was carried out in the Son Llàtzer University Hospital Pain Clinic of Palma de Mallorca, Spain. Ethical approval was obtained from the Balearic Islands Human Research Ethics Committee in January 2017 (CEI-IB, #IB 3341/16 PI). The local ethics review boards, and the study itself was conducted according to standard guidelines. The trial was registered with ClinicalTrials.gov, number NCT03250754. Data from patients with Headache Disorders (HDs), which did not respond to conventional treatment for at least 6 months, referred to the Pain Clinic, between January 2010 and December 2015, were retrospectively examined. To be included, patients had to meet the following criteria: clinical diagnosis of headache (> 12 months) and at least two headaches per month; age ≥ 18 years. Physicians classified patients according to the criteria of the International Headache Society to differentiate between patients with migraine, tension-type headache (TTH), trigeminal autonomic cephalgias (cluster headache and Horton's headache), trigeminal neuralgia (TN), occipital neuralgia, cervicogenic headache and post-surgery headache. The exclusion criteria for patients were headache caused by somatic diseases such as hypertension, meningioma or meningoencephalitis and onset of headache or acupuncture treatment less than 1-year before. Patients continued with routine care (new prophylactic drug treatment (PDT), treatment of acute headache attacks and lifestyle, meditation, exercise and dietary instructions) or, received acupuncture instead of PDT