WGS in sterol and non-sterol genes in polyene resistant lines of Leishmania spp.

Gene IDs were retrieved from TriTrypDB in L. mexicana. Genotype and amino acid changes from variants in sterol genes is provided in S6 Table. A complete list of variants is provided for SNPs (S9 Table) and CNVs (S8 Table). Hom: homozygous; Het: Heterozygous. § This mutation is a pre-existing difference between both copies of the C24SMT gene and is associated with structural changes but not with drug resistance.