PATZ1 is a DNA damage responsive transcription factor that inhibits p53 function

ChEBI2015-03-27 更新2026-07-21 收录

DNA损伤应答

p53信号通路调控

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PATZ1 is a DNA damage responsive transcription factor that inhibits p53 function

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2015-03-27

Inactivation of the Budding Yeast Cohesin Loader Scc2 alters Gene Expression both Globally and in Response to a Single DNA Double Strand Break [ChIP-seq]

基因表达调控

DNA损伤应答

Genome integrity is fundamental for cell survival and cell cycle progression. Important mechanisms for keeping the genome intact are proper sister chromatid segregation, correct gene regulation and ef

NIAID Data Ecosystem60

SNIP1 recruits TET2 to regulate c-MYC target genes and cellular DNA damage response

DNA损伤应答

TET2靶向招募与表观遗传调控

The TET2 DNA dioxygenase regulates gene expression by catalyzing demethylation of 5-methylcytosine, thus epigenetically modulating the genome. TET2 does not contain a sequence-specific DNA binding dom

NIAID Data Ecosystem40

The effect on lincRNA expression by p53 family members.

p53信号通路调控

长链非编码RNA分析

To evaluate the effect on lincRNA expression by p53 family members, we overexpressed p53 family members in H1299 cells and evaluated the lincRNA expression by microarray analysis. lincRNA expression w

NIAID Data Ecosystem10

RasV12 blocks DNA synthesis and DNA damage response

癌症信号传导

DNA损伤应答

Transcriptional profile of RasV12 expressing cells shows an upregulation of RTK signalling genes and a downregulation in genes involved in DNA sintesis and DNA damage response. mRNA expression profile

NIAID Data Ecosystem50

Structure of human microcephalin (MCPH1) tandem BRCT domains in complex with an H2A.X peptide phosphorylated at Ser139 and Tyr142

DNA损伤应答

组蛋白磷酸化

Structure of human microcephalin (MCPH1) tandem BRCT domains in complex with an H2A.X peptide phosphorylated at Ser139 and Tyr142 Descriptor: GLYCEROL, Histone H2A.X peptide, Microcephalin Authors: Si

Protein Data Bank Japan2024-10-30 更新30

PATZ1 is a DNA damage responsive transcription factor that inhibits p53 function

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