Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 16d (high resolution)
收藏Protein Data Bank Japan2024-10-16 更新2026-04-19 收录
下载链接：
https://pdbj.org/mine/summary/8dgy
下载链接
链接失效反馈官方服务：
资源简介：
Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 16d (high resolution) Descriptor: 3C-like proteinase, [(1~{R},2~{R})-2-(cyclohexylmethyl)cyclopropyl]methyl ~{N}-[(2~{S})-1-[[(1~{R},2~{S})-1-[bis(oxidanyl)-oxidanylidene-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate, [(1~{R},2~{R})-2-(cyclohexylmethyl)cyclopropyl]methyl ~{N}-[(2~{S})-1-[[(1~{S},2~{S})-1-[bis(oxidanyl)-oxidanylidene-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate Authors: Lovell, S, Liu, L, Battaile, K.P, Nguyen, H.N, Chamandi, S.D, Picard, H.R, Madden, T.K, Thruman, H.A, Kim, Y, Groutas, W.C, Chang, K.O. Deposit date: 2022-06-24 Release date: 2022-07-06 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Broad-Spectrum Cyclopropane-Based Inhibitors of Coronavirus 3C-like Proteases: Biochemical, Structural, and Virological Studies. Acs Pharmacol Transl Sci, 6, 2023
创建时间：
2022-06-24
