HDAC concentrations in whole hemisphere of mouse brain.

aMeasurements were performed on supernatants of whole left hemispheres of mouse brains from 5XFAD (n = 4) and wild type (n = 2) mice supplemented with QconCAT standards after high-speed centrifugation. Three transitions per Q-peptide were used to calculate concentration for each mouse. Wild type (n = 2) and 5XFAD (n = 4) mice concentrations were averaged and data is presented as mean ± SD of each sample group. Q-peptide transitions are summarized in S6 Table. b, p < 0.05; c, p < 0.01. HDAC concentrations in whole hemisphere of mouse brain.