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Crystals Structure of the SARS-CoV-2 (COVID-19) main protease with inhibitor GC-376

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Protein Data Bank Japan2024-11-13 更新2026-03-21 收录
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Crystals Structure of the SARS-CoV-2 (COVID-19) main protease with inhibitor GC-376 Descriptor: (1R,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, ... Authors: Sacco, M, Ma, C, Chen, Y, Wang, J. Deposit date: 2020-05-03 Release date: 2020-05-20 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease. Cell Res., 30, 2020

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2020-05-03
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