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pre-mRNA splicing order is defined and maintains splicing fidelity across multi-intronic transcripts

NIAID Data Ecosystem2026-05-01 收录

pre-mRNA剪接

剪接保真度

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE232455 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-08-14

剪接体机制

剪接保真度

Purpose: To assess the global impacts of RNaseH domain alleles of Prp8 on the in vivo splice site selection for native introns. Conclusions: Our study reveals functional links between distinct spliceo

NIAID Data Ecosystem50

A Highly Conserved GAD-1 Is Required for Pre-mRNA Splicing and Transcription Elongation by Forming Spliceosome with NineTeen Complex

pre-mRNA剪接

转录延伸机制

Pre-mRNA splicing requires assembly of spliceosome that consists of hundreds of factors forming various dynamic complexes with or without small nuclear RNAs (snRNAs). Systematic identification of the

NIAID Data Ecosystem30

Transcription Rate Strongly Affects Splicing Fidelity and Co-transcriptionality in Budding Yeast

剪接保真度

转录-剪接耦合

The functional consequences for alternative splicing of altering the transcription rate have been the subject of intensive study in mammalian cells but less is known about effects on splicing of chang

NIAID Data Ecosystem20

DDX54 regulates transcriptome dynamics during DNA damage response [4SU-seq]. Homo sapiens

DNA损伤应答

pre-mRNA剪接

The cellular response to genotoxic stress is mediated by a well-characterized network of DNA surveillance pathways. The contribution of posttranscriptional gene regulatory networks to the DNA damage r

NIAID Data Ecosystem40

Biochemical and Genetic Conservation of Fission Yeast Dsk1 and Human SR Protein-Specific Kinase 1

pre-mRNA剪接

酶功能保守性

Arginine/serine-rich (RS) domain-containing proteins and their phosphorylation by specific protein kinases constitute control circuits to regulate pre-mRNA splicing and coordinate splicing with transc

PubMed Central30

pre-mRNA splicing order is defined and maintains splicing fidelity across multi-intronic transcripts

资源简介：

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