BIOGRID CURATED DATA FOR PHB2 (Saccharomyces cerevisiae (S288c))
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资源简介：
Protein-Protein, Genetic, and Chemical Interactions for PHB2 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Subunit of the prohibitin complex (Phb1p-Phb2p); prohibitin is a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation; prohibitin deficiency induces a mitochondrial unfolded protein response (mtUPR)
蛋白-蛋白、遗传和化学相互作用数据集，针对酿酒酵母（S288c）中的PHB2（由BioGRID整理，https://thebiogrid.org）；定义：禁止素复合体（Phb1p-Phb2p）的亚基；禁止素是一种1.2兆道尔顿的环状线粒体内膜伴侣蛋白，能够稳定新生成的蛋白质；是复制寿命的决定因素；参与线粒体分离；禁止素缺乏可诱导线粒体未折叠蛋白反应（mtUPR）
提供机构：
BioGRID Project
