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Gene expression based profiling of pleomorphic xanthoastrocytoma highlights two prognostic subgroups

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE168904
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First comprehensive analysis highlighting distinct molecular subgroups of PXA. The DEGs between two clusters may potentially be used for developing histology independent classification scheme, prognostication and suggest prospective therapeutic targets Genome-wide expression profiling of 14 PXA and 6 APXAs was performed by microarray. Amongst differentially expressed genes ( DEGs), Cyclin Dependent Kinase 14 (CDK 14) and Mitochondrial Fission Process 1 (MTFP 1) were validated by qRT-PCR.
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2021-12-15
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