Generation of midbrain dopaminergic (mDA) neurons from human pluripotent stem cells provides a platform for inquiry into basic and translational studies of Parkinsonâs disease (PD). However, heterog
Ptf1a has been shown to be necessary for determining an inhibitory interneuronal fate in many regions of the nervous system. In this study, we aim to investigate the sufficiency of Ptf1a to cell-auton
Defects in DNA repair frequently lead to neurodevelopmental and neurodegenerative diseases, underscoring the particular importance of DNA repair in long-lived post-mitotic neurons. The cellular genome
Compared to laboratory environments, complex natural environments promote brain cell proliferation and neurogenesis. Predators are one important feature of many natural environments, and, in the labor
Additional file 1: Table S1. List of proteins detected by tandem mass spectrometry iTRAQ in technical duplicates of WT and Ts1Cje synaptoneurosomes (SNs). Quantification is referred to one of the WT s
