DNA methylation analysis of colorectal cancer SW48/YB5 cell line treated with the HH1 compound
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE104998
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YB5 is a colon cancer cell line derived from the SW48 colon cancer cell line and contains a DNA methylated and silenced CMV promoter driving expression of a GFP reporter. The cells were treated with 10 micromolar concentration of the HH1 compound or with DMSO as a control. Reduced representation bisulfite sequencing (RRBS) was performed after the treatment to analyze DNA methylation at CpG sites. Biological triplicates were performed for HH1 and DMSO control. Untreated cells were analyzed in a biological duplicate.
创建时间:
2021-07-25



