Glycerol monooleate mitigates PEDV-induced intestinal injury in piglets by enhancing antioxidant capacity, strengthening immune function, and modulating intestinal microbiota

This study investigated the protective effects of glycerol monooleate against porcine epidemic diarrhea virus induced intestinal injury in neonatal piglets. Twentyfour 7 days old piglets were divided into four groups: CTRL, GMO, PEDV, and PEDV and GMO. From D 4 to 10, piglets in GMO groups received 100 mg/kg GMO supplementation. Piglets in PEDV groups were challenged with PEDV per piglet on D 8. Blood and intestinal samples were collected from all piglets after euthanasia on D 11 to assess intestinal morphology, oxidative stress status, inflammatory response, and intestinal microbiota.