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The role of Phc1 in organizing the chromatin interactions of the Nanog locus in ESCs. The role of Phc1 in organizing the chromatin interactions of the Nanog locus in ESCs

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA649985
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To look into whether Phc1 is involved in organizing the chromatin interactions of the Nanog locus in ESCs. We performed circularized chromosome conformation capture sequencing (4C-seq) of the genome-wide regions interacting with the Nanog locus in both Phc1+/+ and Phc1-/- mESCs. By doing so, we showed that ablation of Phc1 impaired the genome-wide chromatin interactions of the Nanog locus in mESCs. Overall design: 4C-seq of the genome-wide regions interacting with the Nanog locus in both Phc1+/+ and Phc1-/- mESCs.
创建时间:
2020-07-31
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