DYRK1A bound to a harmine derivative
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DYRK1A bound to a harmine derivative Descriptor: 4-(7-methoxy-1-methyl-9H-beta-carbolin-9-yl)butanamide, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, TETRAETHYLENE GLYCOL Authors: Khamrui, S, Lazarus, M.B. Deposit date: 2019-11-05 Release date: 2020-02-12 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Synthesis and Biological Validation of a Harmine-Based, Central Nervous System (CNS)-Avoidant, Selective, Human beta-Cell Regenerative Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase A (DYRK1A) Inhibitor. J.Med.Chem., 63, 2020
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2019-11-05
