Expression data from wt, Lkb1 conditional knock out and LPS treated DC. Expression data from wt, Lkb1 conditional knock out and LPS treated DC

To dissect the molecular mechanism by which Lkb1 controls DC function, we performed transcriptional profiling of DCs sorted from Lkb1f/f, LPS-treated mice and Cd11cCreLkb1f/f mice. We used microarrays to detail the global programme of gene expression underlying cellularisation and identified Overall design: DCs were sorted from spleen of Lkb1f/f mice, LPS-treated mice, Cd11cCreLkb1f/f mice for RNA extraction and hybridization