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Neuropilin-1 b1 domain in complex with EG01377; 2.8 Angstrom structure

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Neuropilin-1 b1 domain in complex with EG01377; 2.8 Angstrom structure Descriptor: (2~{S})-2-[[3-[[5-[4-(aminomethyl)phenyl]-1-benzofuran-7-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid, Neuropilin-1, trifluoroacetic acid Authors: Yelland, T, Djordjevic, S, Selwood, D, Zachary, I, Frankel, P. Deposit date: 2018-01-31 Release date: 2018-10-17 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.811 Å) Cite: Small Molecule Neuropilin-1 Antagonists Combine Antiangiogenic and Antitumor Activity with Immune Modulation through Reduction of Transforming Growth Factor Beta (TGF beta ) Production in Regulatory T-Cells. J. Med. Chem., 61, 2018
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2018-01-31
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