Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 36
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Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 36 Descriptor: 4-fluoro-N-{(2E)-6-{[4-(2-hydroxypropan-2-yl)piperidin-1-yl]methyl}-1-[cis-4-(propan-2-ylcarbamoyl)cyclohexyl]-1,3-dihydro-2H-benzimidazol-2-ylidene}benzamide, ALK tyrosine kinase receptor, GLYCEROL Authors: Whittington, D.A, Epstein, L.F, Chen, H. Deposit date: 2012-06-20 Release date: 2012-07-11 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2 Å) Cite: The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer. J.Med.Chem., 55, 2012
创建时间：
2012-06-20
