Number of loci with at least one SNP significantly associated with AMD in the 100,000 SNP genome-wide scan of the AREDS cohort*.

*Significant association was defined as P?4.**An adjacent SNP associated with AMD refers to the nearest centromeric and telomeric SNP within 50 kb or less genotyped on the Illumina 100,000 SNP genome-wide scan with a p-value��0.01 for association with AMD. SNPs meeting this criteria are referred to as ��confirmed��.***SNPs associated with AMD were arbitrarily defined as being in separate loci if they were located at least 500 kb from each other.****One of these 58 SNPs (rs7497988, now called rs3985626) could not be genotyped on the Illumina platform and was not studied. The already known and artifact categories were not genotyped, leaving 57 AREDS SNPs in 46 loci.