Effects of prebiotic xylo-oligosaccharide on PWD piglet performance and gut health

While the effects of XOS in healthy weaning pigs have been well-document in re-cent years, fewer studies have examined its impact in pathogen-challenged piglets. Notably, no studies to date have assessed the effects of XOS in weaning piglets experiencing PWD under commercial farm conditions that reflect real-world production settings. Therefore, the objectives of this study were to investigate the effects of XOS supplementation on performance, gut microbiome composition, immune response, gut barrier integrity, intestinal architecture, and goblet cell (GC) expression in weaning piglets exhibiting self-limiting PWD that did not require antibiotic or other therapeutic intervention.