b, VPA- or TSA-treated groups differ significantly from their respective controls (zero, a) at the P 0.05 level (Mann-Whitney test); TSA, trichostatin A; VPA, valproic acid; n, 1000 cells per experime
The in situ detection of caspase-3 activity has applications in the imaging and monitoring of multiple pathologies, notably cancer. A series of cell penetrating FRET-based fluorogenic substrates were
aMice (n = 6/group) were i.n. infected with 104 PFU of VK627, rVK627E, TsE627, rTsE627K.bMice were euthanized on 3 day p.i. and 5 day p.i., and three thymuses per group per time point were prepared fo
