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RNA sequence of CD49f-positive mesenchymal populations in dermis of neonatal mice

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE135471
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We defined CD49f-high, CD49f-low and CD49f-neg mesenchymal subpopulations in the dermis. Transcriptome analysis revealed that CD49fhigh cells highly express gene regulatory network of neural crest cells, while CD49flow cells were enriched with melanocyte lineage development and maintenance related genes. The identity and function of above cell populations were further verified by lineage tracing. Skin mesenchymal subpopulations with different expression level of CD49f were FACS sorted and sequenced.
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2019-08-16
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