Crystal structure of HCV NS3/4A protease in complex with ITMN-191
收藏Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/3m5l
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of HCV NS3/4A protease in complex with ITMN-191 Descriptor: (2R,6S,12Z,13aS,14aR,16aS)-6-[(tert-butoxycarbonyl)amino]-14a-[(cyclopropylsulfonyl)carbamoyl]-5,16-dioxo-1,2,3,5,6,7,8 ,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 4-fluoro-2H-isoindole-2-carboxylate, NS3/4A, SULFATE ION, ... Authors: Schiffer, C.A, Romano, K.P. Deposit date: 2010-03-12 Release date: 2010-11-24 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Drug resistance against HCV NS3/4A inhibitors is defined by the balance of substrate recognition versus inhibitor binding. Proc.Natl.Acad.Sci.USA, 107, 2010
创建时间：
2010-03-12
