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Direct conversion of normal and patient human fibroblasts into neuronal cells

ChEBI2015-07-28 更新2026-07-12 收录

细胞重编程

神经疾病模型

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-69480 数据链接链接失效反馈

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资源简介：

Direct conversion of normal and patient human fibroblasts into neuronal cells

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创建时间：

2015-07-28

细胞重编程

β细胞分化

We reprogrammed human foreskin fibroblasts towards beta-like cells via adenovirus-mediated sequential introduction of five transcription factors (Ngn3, Pdx1, Mafa. pax4, Nkx2-2). At day 11 after initi

NIAID Data Ecosystem60

C2C12 murine myoblast cell line and 48 h 10 uM BIO treated C2C12 cellulate. Mus musculus

细胞重编程

心肌细胞去分化机制

In urodele amphibians, limb regeneration involves the dedifferentiation of muscle myotubes into single cells that may acquire pluripotent potential. We have employed small molecules (myoseverin and BI

NIAID Data Ecosystem50

Multigene transfection efficiency and Myh6 + and Tnnt2 + cell induction rate.

细胞重编程

心肌细胞分化

*>30,000 total cells per group were analyzed. †>100 multigene-transfected cells were analyzed. ‡Data are expressed as (mean ± standard error of mean)%. §More than 1000 total cells per group were analy

NIAID Data Ecosystem40

Direct reprogramming of mouse fibroblasts into functional skeletal muscle progenitors. Mus musculus

细胞重编程

骨骼肌细胞

Skeletal muscle harbors quiescent stem cells termed satellite cells and proliferative progenitors termed myoblasts, which play pivotal roles during muscle regeneration. However, current technology doe

NIAID Data Ecosystem50

Comparison of hiPSCs, hESCs and fibroblasts

细胞重编程

基因表达谱比较分析

In our study, PRDM14 and NFRkB were found to enhance the reprogramming of human fibroblasts to hiPSCs in the presence of OCT4, SOX2, KLF4, with/without c-MYC (OSK/OSKC). To examnie if the obtained hiP

NIAID Data Ecosystem50

Direct conversion of normal and patient human fibroblasts into neuronal cells

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