rAAV expressing COBRA HA generates protective and durable immune response
收藏NIAID Data Ecosystem2026-05-10 收录
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https://immport.org/shared/study/SDY2733
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资源简介：
Mice and ferrets were vaccinated with varying dosages of recombinant adenovirus-associated virus (rAAV) vector expressing a computationally optimized broadly reactive antigen Y2 (COBRA)-derived influenza H1 hemagglutinin (HA). Single administration of a rAAV COBRA HA induces neutralizing and broadly protective antibodies in animals. The data supports the utility of viral vector as a potential approach to improve the influenza seasonal vaccines.
创建时间：
2025-10-30
