Dietary succinate reduces fat deposition through gut microbiota and lipid metabolism

Succinate has been shown to be a nutritional supplement of potential benefit with a diverse range of physiological functions, including antioxidant, antimicrobial and immunomodulatory properties. However, it is unknown whether succinate supplementation regulates lipid metabolism of chickens. The aim of this research was to explore how succinate affects fat deposition and the mechanism in yellow-feathered broilers and to determine the most appropriate level of succinate supplementation in the diet. 640 one-day-old yellow-feathered broilers were divided by a random method into four groups with 8 replicates, 20 broilers per replicate. Basal diet was given to the control group (CON). The experimental broilers were fed diets containing 0.2% (L), 0.4% (M), or 0.6% (H) succinate and the study was lasted for 3 weeks.