RNA-Seq of M1 activated ErbB4-null and WT bone-marrow macrophages.
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https://www.ncbi.nlm.nih.gov/sra/SRP308860
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资源简介：
We tested the hypothesis that NRG4/ErbB4 signaling regulates cytokine production in macrophages. Loss of ErbB4 in bone-marrow derived macrophages results in elevated pro-inflammatory cytokine production. These results demonstrate a feedback mechanism by which growth factor signaling can limit immune cells activity. Overall design: Gene expression profiling from M1 activated bone-marrow macrophages from 6 LysMCre/ErbB4-floxxed (KO) and 6 littermate ErbB4-floxxed (WT) controls. Samples are pair-matched with 1 KO and 1 WT from separate litters.
创建时间：
2021-04-10
