Genome-wide mapping of binding of HDAC1/HDAC2 and H3K9/14Ac modification in control and Tet2/Tet3-deficient B cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE137666
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We report the genome-wide accumulation of HDAC1, HDAC2 and H3K9/14Ac in B cells. We found that the binding of HDAC1 and HDAC2 was observed mainly on proximal promoters, suggesting a redundant role of these HDACs in transcriptional regulation. This study provides a basis for the comprehensive understanding of Tet2/Tet3-HDACs-mediated B cell regulation. Examination of global binding of HDAC1/HDAC2 and H3K9/14Ac modification in control and Tet2/Tet3-deficient B cells
创建时间:
2020-07-08



