Nrp1 expression on adoptively transferred CD8+ T cells does not influence the efficacy of immunotherapy for leukemia.

B6 or Alb∶Gag recipient mice were inoculated with FBL leukemia. Seven days later, tumor-bearing recipients were infused with WT or Nrp1-deficient Gag-specific CD8+ T cells. Recipient survival was tracked for 40 days, and results pooled from 2 separate experiments are depicted in the graph showing percent survival (y-axis) over time in days (x-axis), with a total 10 mice in each treatment group. Data from B6 and Alb∶Gag groups were compared and P values are indicated (ns = not significant).