The Pediatric Rescue Manifold v1.3: Expanded HDR-512 Structural Cohort (10 Lethal Targets)
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Comprehensive pediatric rescue manifold expanded to 10 lethal oncogenic drivers: 1. H3.3 K27M (DIPG). 2. MYCN (Neuroblastoma). 3. ALK F1174L (Neuroblastoma). 4. FLI1 (Ewing Sarcoma). 5. SMARCB1 (Rhabdoid Tumors). 6. CTNNB1 (Hepatoblastoma). 7. BRAF Fusion kinase domain. 8. ACVR1 R206H (DIPG). 9. EWS-FLI1 Fusion (Ewing Sarcoma Chimeric Driver). 10. IDH1 R132H (Glioma).
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Zenodo创建时间：
2026-04-25
