Unimod
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Unimod is a community-supported, comprehensive database of protein modifications for mass spectrometry applications. The aim is to provide accurate and verifiable values, derived from elemental compositions, for the mass differences introduced by all types of natural and artificial modifications. Other important information includes any mass change, (neutral loss), that occurs during MS/MS analysis, and site specificity, (which residues are susceptible to modification and any constraints on the position of the modification within the protein or peptide).
Unimod是一个由社区支持的、面向质谱(mass spectrometry)应用的综合性蛋白质修饰数据库。其宗旨是为各类天然与人工修饰所引入的质量差值,提供基于元素组成推导得出的准确且可验证的数值。此外,该数据库还涵盖了串联质谱(MS/MS)分析过程中发生的任意质量变化(即中性丢失(neutral loss)),以及位点特异性信息:具体为哪些氨基酸残基易发生修饰,以及修饰在蛋白质或肽段内的位置所受的各类约束条件。




