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Expression data from proliferating and quiescent adult hippocampal neural stem and progenitor cells

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE158658
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We have characterized the transcriptome of adult rat hippocampal neural stem and progenitor cell (NSPC) cultures. The NSPCs cultures can be reversibly arrested by the quiescence-promoting signal BMP4. We provide expression data from NSPCs grown as neurospheres for 4 days in vitro in the presence of FGF2 (proliferating NSPCs) or FGF2+BMP4 (quiescent NSPCs) showing that entry into quiescence involves major changes in the transcriptional profile of the cells. 6 RNA samples were analyzed. Total RNA was isolated from proliferating NSPCs cultured in FGF2 and quiescent NSPCs cultured in FGF2+BMP4, 3 biological replicates for each condition.
创建时间:
2020-10-01
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